Latest News and Announcements

Visit our new Lab Webpage

hakyimlab.org

Read the full post


Winners of U4C Challenge leverage PrediXcan

Two of the 5 winners of NCI's "Up for a Challenge? (U4C) Stimulating Innovation in Breast Cancer Genetic Epidemiology" leveraged PrediXcan (individual and summary based) approach for their discoveries.

https://epi.grants.cancer.gov/events/u4c/winners.html

Read the full post


MetaXcan manuscript on bioRxiv

MetaXcan: Summary Statistics Based Gene-Level Association Method Infers Accurate PrediXcan Results [link]

Read the full post


PrediXcan among top 3 in #TBICRI16/methods

We are elated that our PrediXcan paper was chosen one of the top three papers in the category of "Methods for Genetic Discovery" in the "Translational Bioinformatics 2016: The Year in Review" list. This was curated by Russ Altman and the AMIA Student Working Group. Congratulations to everyone who worked hard to get this done. [link]

Read the full post


Find our manuscript on genetic architecture of gene expression across tissues on BioRxiv

Survey of the Heritability and Sparsity of Gene Expression Traits Across Human Tissues [link]

Read the full post


Find our Bipolar Disorder manuscript on BioRxiv

A preprint of our manuascript "Genetic predictors of gene expression associated with risk of bipolar disorder" was posted on BioRxiv [link

Read the full post


Multiple Openings in Genomic Data Science Lab

Are you passionate about science and know how to navigate big data? Or want to learn how to tame big data in a collegial environment? Then join me in building a Genomic Data Science Laboratory.

Read the full post


Robert Elston Best Paper Award for our OmicKriging paper

Plaque autographed by Robert Elston himself! [link]

Read the full post


NIMH R01 awarded

Imlab was awarded with the NIMH R01 grant for "developing advanced computational, bioinformatic, and statistical tools to determine the functional relevance of genetic variants associated with mental disorders of complex etiologies identified through genome-wide association or sequencing studies".

http://grants.nih.gov/grants/guide/pa-files/PAR-13-391.html 

Read the full post


Now hiring pre and post doctoral candidates

We are looking for a highly motivated quantitative scientist interested in directing their career toward interdisciplinary biomedical research. This is a great time to veer your career into this rapidly growing area since we are facing a shortage of scientists with the analytical and computational background to take advantage of the enormous amount of genomic and health data generated. Two large initiatives Big Data to Knowledge and Precision Medicine by the NIH show the commitment of the US government in investing in these areas.

Read the full post


Invited talk at the ASHG Wed 10/7/11am-1pm

Haky will be giving a talk on MetaXcan in the invited session "Secure, Efficient, and Scalable Computational Genetics via Summary Statistics" at the ASHG meeting in Baltimore (Wednesday, October 07, 2015 from 11am to 1pm).

Read the full post


Press release for PrediXcan

Kevin Jiang's blog post: http://sciencelife.uchospitals.edu/2015/08/10/new-computational-method-predicts-genes-likely-to-be-causal-in-disease/

The press release can be found here: http://www.uchospitals.edu/news/2015/20150810-predixcan.html

Some places that have rerun the press release:

Read the full post


PrediXcan published online in Nature Genetics

A gene-based association method for mapping traits using reference transcriptome data

Eric R Gamazon, Heather E Wheeler, Kaanan P Shah, Sahar V Mozaffari, Keston Aquino-Michaels, Robert J Carroll, Anne E Eyler, Joshua C Denny, GTEx Consortium, Dan L Nicolae, Nancy J Cox & Hae Kyung Im

Read the full post


PrediXcan manuscript accepted for publication in Nature Genetics

PrediXcan is a gene-based association test that prioritizes genes that are likely to be causal for the phenotype.

https://github.com/hakyimlab/PrediXcan

http://biorxiv.org/content/early/2015/06/17/020164

Read the full post


NIDA P50 Pilot Grant Awarded

We were awarded one of the Pilot Project Grant Awards for NIDA P50 Grant P50DA037844 to build a web resource to integrate discoveries in rat and human phenotypes.

Read the full post


Genomic Privacy #JSM2014 Slides

Genomic Privacy #JSM2014 Slides

Read the full post


Poly-Omic Prediction of Complex Traits: OmicKring online

Our paper 'Poly-Omic Prediction of Complex Traits: OmicKring' is available online 

Read the full post


DRTC pilot grant awarded

The Diabetes Research and Training Center has awarded a Pilot and Feasibility grant for our proposal entitled "Systems Approach to Discover Biological Mechanisms of Complex Traits". P30 DK020595

Read the full post


K12 Award

Haky has been selected as a University of Chicago Paul Calabresi Clinical Oncology K12 Scholar. The award period is 08/01/13 to 07/31/15. K12CA139160.

Read the full post